6F56
Mutant of Human N-myristoyltransferase with bound myristoyl-CoA
Summary for 6F56
| Entry DOI | 10.2210/pdb6f56/pdb |
| Descriptor | Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | n-myristoyltransferase, mutant, parasite, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 195224.67 |
| Authors | Brenk, R.,Kehrein, J.,Kersten, C. (deposition date: 2017-11-30, release date: 2019-03-20, Last modification date: 2024-01-17) |
| Primary citation | Kersten, C.,Fleischer, E.,Kehrein, J.,Borek, C.,Jaenicke, E.,Sotriffer, C.,Brenk, R. How To Design Selective Ligands for Highly Conserved Binding Sites: A Case Study UsingN-Myristoyltransferases as a Model System. J.Med.Chem., 2019 Cited by PubMed: 31423787DOI: 10.1021/acs.jmedchem.9b00586 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9401987668 Å) |
Structure validation
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