6F4M

Human JMJD5 in its apo form.

6F4M の概要

• エントリーDOI: 10.2210/pdb6f4m/pdb
• 関連するPDBエントリー: 6F4N 6F4O 6F4P 6F4Q 6F4R 6F4S 6F4T
• 分子名称: JmjC domain-containing protein 5 (2 entities in total)
• 機能のキーワード: oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, jmjc, jmjc domain, lysine-specific demethylase 8, jmjc domain-containing protein 5, arginyl c-3 hydroxylase, jmjd5, kdm8, oxygenase, hypoxia, dna-binding, metal-binding, translation, dsbh, facial triad, cytoplasm, jmjc hydroxylase, jmjc demethylase, kdms, post-translational modifications, ptm, beta-hydroxylation, hydroxylation, arginine hydroxylation, rcc1 domain-containing protein 1, rccd1, regulator of chromosome condensation, 40s ribosomal protein s6, rps6, ribosome biogenesis, transcription, epigenetic regulation, signaling, development, cell structure, transcription activator/inhibitor, phosphorylation, cancer, polymorphism
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus : Q8N371
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27133.61

構造登録者

Chowdhury, R.,Islam, M.S.,Schofield, C.J. (登録日: 2017-11-29, 公開日: 2018-04-04, 最終更新日: 2024-01-17)

• 主引用文献: Wilkins, S.E.,Islam, S.,Gannon, J.M.,Markolovic, S.,Hopkinson, R.J.,Ge, W.,Schofield, C.J.,Chowdhury, R.; JMJD5 is a human arginyl C-3 hydroxylase.; Nat Commun, 9:1180-1180, 2018; PubMed: 29563586; DOI: 10.1038/s41467-018-03410-w

実験手法

X-RAY DIFFRACTION (1.705 Å)