6F3C
The cytotoxic [Pt(H2bapbpy)] platinum complex interacting with the CGTACG hexamer
Summary for 6F3C
Entry DOI | 10.2210/pdb6f3c/pdb |
Descriptor | DNA (5'-D(*GP*TP*AP*CP*G)-3'), MAGNESIUM ION, [Pt(H2bapbpy)] platinum, ... (5 entities in total) |
Functional Keywords | drug-dna complex, four-way junction, dna |
Biological source | synthetic construct More |
Total number of polymer chains | 4 |
Total formula weight | 7753.73 |
Authors | Ferraroni, M.,Bazzicalupi, C.,Gratteri, P.,Papi, F. (deposition date: 2017-11-28, release date: 2019-05-29, Last modification date: 2024-01-17) |
Primary citation | van Rixel, V.H.S.,Busemann, A.,Wissingh, M.F.,Hopkins, S.L.,Siewert, B.,van de Griend, C.,Siegler, M.A.,Marzo, T.,Papi, F.,Ferraroni, M.,Gratteri, P.,Bazzicalupi, C.,Messori, L.,Bonnet, S. Induction of a Four-Way Junction Structure in the DNA Palindromic Hexanucleotide 5'-d(CGTACG)-3' by a Mononuclear Platinum Complex. Angew.Chem.Int.Ed.Engl., 58:9378-9382, 2019 Cited by PubMed: 31046177DOI: 10.1002/anie.201814532 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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