6F2N
Crystal structure of BCII Metallo-beta-lactamase in complex with KDU197
Summary for 6F2N
Entry DOI | 10.2210/pdb6f2n/pdb |
Related | 5JMX 6EUM 6EW3 6EWE |
Descriptor | Metallo-beta-lactamase type 2, ZINC ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | antimicrobial resistance, metallo beta lactamase, inhibitor, hydrolase |
Biological source | Bacillus cereus |
Total number of polymer chains | 1 |
Total formula weight | 25542.82 |
Authors | McDonough, M.A.,El-Hussein, A.,Schofield, C.J.,Zhang, D.,Brem, J. (deposition date: 2017-11-24, release date: 2018-10-03, Last modification date: 2024-01-17) |
Primary citation | Zhang, D.,Markoulides, M.S.,Stepanovs, D.,Rydzik, A.M.,El-Hussein, A.,Bon, C.,Kamps, J.J.A.G.,Umland, K.D.,Collins, P.M.,Cahill, S.T.,Wang, D.Y.,von Delft, F.,Brem, J.,McDonough, M.A.,Schofield, C.J. Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases. Bioorg. Med. Chem., 26:2928-2936, 2018 Cited by PubMed: 29655609DOI: 10.1016/j.bmc.2018.02.043 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.149 Å) |
Structure validation
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