6EYI

E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand BW69669

6EYI の概要

• エントリーDOI: 10.2210/pdb6eyi/pdb
• 分子名称: E-selectin, 2-acetamido-2-deoxy-beta-D-glucopyranose, (2~{R})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[(1~{R},2~{R})-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxycyclohexyl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-propanoic acid, ... (5 entities in total)
• 機能のキーワード: cell adhesion, cell-adhesion molecule, c-type lectin, inflammation, leukocyte, glycomimetic, catch-bond
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33553.10

構造登録者

Jakob, R.P.,Zihlmann, P.,Preston, R.C.,Varga, N.,Ernst, B.,Maier, T. (登録日: 2017-11-13, 公開日: 2018-11-21, 最終更新日: 2024-01-17)

• 主引用文献: Varga, N.,Zihlmann, P.,Preston, R.C.,Jakob, R.P.,Maier, T.,Ernst, B.; E-selectin lectin with different glycomimetic ligands; To Be Published,

実験手法

X-RAY DIFFRACTION (2.04 Å)