6ERA
Crystal structure of cyclohexanone monooxygenase mutant (F249A, F280A and F435A) from Rhodococcus sp. Phi1 bound to NADP+
Summary for 6ERA
Entry DOI | 10.2210/pdb6era/pdb |
Descriptor | Cyclohexanone monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total) |
Functional Keywords | monooxygenase, rossmann fold, fad, nadp+, lactone, dihydrocarvone, flavoprotein |
Biological source | Rhodococcus sp. Phi1 |
Total number of polymer chains | 2 |
Total formula weight | 124480.77 |
Authors | Karuppiah, V.,Scrutton, N.S. (deposition date: 2017-10-17, release date: 2018-09-26, Last modification date: 2024-01-17) |
Primary citation | Messiha, H.L.,Ahmed, S.T.,Karuppiah, V.,Suardiaz, R.,Ascue Avalos, G.A.,Fey, N.,Yeates, S.,Toogood, H.S.,Mulholland, A.J.,Scrutton, N.S. Biocatalytic Routes to Lactone Monomers for Polymer Production. Biochemistry, 57:1997-2008, 2018 Cited by PubMed: 29533655DOI: 10.1021/acs.biochem.8b00169 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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