6ERA

Crystal structure of cyclohexanone monooxygenase mutant (F249A, F280A and F435A) from Rhodococcus sp. Phi1 bound to NADP+

6ERA の概要

• エントリーDOI: 10.2210/pdb6era/pdb
• 分子名称: Cyclohexanone monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: monooxygenase, rossmann fold, fad, nadp+, lactone, dihydrocarvone, flavoprotein
• 由来する生物種: Rhodococcus sp. Phi1
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 124480.77

構造登録者

Karuppiah, V.,Scrutton, N.S. (登録日: 2017-10-17, 公開日: 2018-09-26, 最終更新日: 2024-01-17)

• 主引用文献: Messiha, H.L.,Ahmed, S.T.,Karuppiah, V.,Suardiaz, R.,Ascue Avalos, G.A.,Fey, N.,Yeates, S.,Toogood, H.S.,Mulholland, A.J.,Scrutton, N.S.; Biocatalytic Routes to Lactone Monomers for Polymer Production.; Biochemistry, 57:1997-2008, 2018; PubMed: 29533655; DOI: 10.1021/acs.biochem.8b00169

実験手法

X-RAY DIFFRACTION (2.49 Å)