6EPW

The ATAD2 bromodomain in complex with compound UZH-DU32

Summary for 6EPW

• Entry DOI: 10.2210/pdb6epw/pdb
• Descriptor: ATPase family AAA domain-containing protein 2, (2~{R})-~{N}-[5-[3,5-bis(oxidanyl)phenyl]-4-ethanoyl-1,3-thiazol-2-yl]-2-carbamimidamido-propanamide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: bromodomain, atad2, inhibitor, complex, cytosolic protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16276.36

Authors

Sledz, P.,Caflisch, A. (deposition date: 2017-10-12, release date: 2018-10-31, Last modification date: 2019-11-13)

• Primary citation: Sledz, P.; Hitting a moving target: simulation and crystallography study of ATAD2 bromodomain blockers; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.924 Å)