6EPR

The ATAD2 bromodomain in complex with compound UZH-DS15

Summary for 6EPR

• Entry DOI: 10.2210/pdb6epr/pdb
• Descriptor: ATPase family AAA domain-containing protein 2, (~{N}~{Z},2~{R})-~{N}-[5-(5-azanylpyridin-3-yl)-4-ethanoyl-3~{H}-1,3-thiazol-2-ylidene]-1-[2-[4,4-bis(fluoranyl)cyclohexyl]ethyl]piperazine-2-carboxamide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: bromodomain, atad2, inhibitor, complex, cytosolic protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16042.16

Authors

Sledz, P.,Caflisch, A. (deposition date: 2017-10-12, release date: 2018-10-31, Last modification date: 2019-11-13)

• Primary citation: Sledz, P.; Hitting a moving target: simulation and crystallography study of ATAD2 bromodomain blockers; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.053 Å)