6ELC

Crystal Structure of O-linked Glycosylated VSG3

6ELC の概要

• エントリーDOI: 10.2210/pdb6elc/pdb
• 分子名称: Variant surface glycoprotein, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: trypanosome, vsg, sleeping sickness, antigen, immune system
• 由来する生物種: Trypanosoma brucei brucei
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 54863.23

構造登録者

Stebbins, C.E. (登録日: 2017-09-28, 公開日: 2018-07-11, 最終更新日: 2022-03-30)

• 主引用文献: Pinger, J.,Nesic, D.,Ali, L.,Aresta-Branco, F.,Lilic, M.,Chowdhury, S.,Kim, H.S.,Verdi, J.,Raper, J.,Ferguson, M.A.J.,Papavasiliou, F.N.,Stebbins, C.E.; African trypanosomes evade immune clearance by O-glycosylation of the VSG surface coat.; Nat Microbiol, 3:932-938, 2018; PubMed: 29988048; DOI: 10.1038/s41564-018-0187-6

実験手法

X-RAY DIFFRACTION (1.41 Å)