6EGT

Structure of RVFV envelope protein Gc in postfusion conformation in complex with MES

Summary for 6EGT

Entry DOI	10.2210/pdb6egt/pdb
Descriptor	Glycoprotein, beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	fusion protein viral envelope lipid interaction viral fusion, viral protein
Biological source	Rift valley fever virus
Total number of polymer chains	3
Total formula weight	174260.89
Authors	Guardado-Calvo, P.,Rey, F.A. (deposition date: 2017-09-12, release date: 2017-11-01, Last modification date: 2024-01-17)
Primary citation	Guardado-Calvo, P.,Atkovska, K.,Jeffers, S.A.,Grau, N.,Backovic, M.,Perez-Vargas, J.,de Boer, S.M.,Tortorici, M.A.,Pehau-Arnaudet, G.,Lepault, J.,England, P.,Rottier, P.J.,Bosch, B.J.,Hub, J.S.,Rey, F.A. A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion. Science, 358:663-667, 2017 Cited by PubMed: 29097548 DOI: 10.1126/science.aal2712 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation