6EGR

Crystal structure of Citrobacter freundii methionine gamma-lyase with V358Y replacement

Summary for 6EGR

Entry DOI	10.2210/pdb6egr/pdb
Descriptor	Methionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, TRIETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywords	methionine gamma-lyase, lyase
Biological source	Citrobacter freundii
Total number of polymer chains	1
Total formula weight	43536.28
Authors	Revtovich, S.V.,Demitri, N.,Raboni, S.,Nikulin, A.D.,Morozova, E.A.,Demidkina, T.V.,Storici, P.,Mozzarelli, A. (deposition date: 2017-09-12, release date: 2018-10-10, Last modification date: 2024-01-17)
Primary citation	Raboni, S.,Revtovich, S.,Demitri, N.,Giabbai, B.,Storici, P.,Cocconcelli, C.,Faggiano, S.,Rosini, E.,Pollegioni, L.,Galati, S.,Buschini, A.,Morozova, E.,Kulikova, V.,Nikulin, A.,Gabellieri, E.,Cioni, P.,Demidkina, T.,Mozzarelli, A. Engineering methionine gamma-lyase from Citrobacter freundii for anticancer activity. Biochim Biophys Acta Proteins Proteom, 1866:1260-1270, 2018 Cited by PubMed: 30268810 DOI: 10.1016/j.bbapap.2018.09.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation