6EAY

Structural Basis for Broad Neutralization of Ebolaviruses by an Antibody Targeting the Glycoprotein Fusion Loop

Summary for 6EAY

Entry DOI	10.2210/pdb6eay/pdb
Descriptor	CA45 light chain, CA45 heavy chain, Envelope glycoprotein, ... (6 entities in total)
Functional Keywords	ebolavirus, glycoprotein, cross-protective antibody, broadly neutralizing antibody, ca45, fusion loop, cross-reactive, filovirus, viral protein
Biological source	Macaca fascicularis More
Total number of polymer chains	4
Total formula weight	104257.06
Authors	Janus, B.M.,Ofek, G. (deposition date: 2018-08-03, release date: 2018-10-10, Last modification date: 2023-10-11)
Primary citation	Janus, B.M.,van Dyk, N.,Zhao, X.,A Howell, K.,Soto, C.,Aman, M.J.,Li, Y.,Fuerst, T.R.,Ofek, G. Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein fusion loop. Nat Commun, 9:3934-3934, 2018 Cited by PubMed: 30258051 DOI: 10.1038/s41467-018-06113-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.72 Å)

Structure validation