6EAY

Structural Basis for Broad Neutralization of Ebolaviruses by an Antibody Targeting the Glycoprotein Fusion Loop

6EAY の概要

• エントリーDOI: 10.2210/pdb6eay/pdb
• 分子名称: CA45 light chain, CA45 heavy chain, Envelope glycoprotein, ... (6 entities in total)
• 機能のキーワード: ebolavirus, glycoprotein, cross-protective antibody, broadly neutralizing antibody, ca45, fusion loop, cross-reactive, filovirus, viral protein
• 由来する生物種: Macaca fascicularis; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 104257.06

構造登録者

Janus, B.M.,Ofek, G. (登録日: 2018-08-03, 公開日: 2018-10-10, 最終更新日: 2023-10-11)

• 主引用文献: Janus, B.M.,van Dyk, N.,Zhao, X.,A Howell, K.,Soto, C.,Aman, M.J.,Li, Y.,Fuerst, T.R.,Ofek, G.; Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein fusion loop.; Nat Commun, 9:3934-3934, 2018; PubMed: 30258051; DOI: 10.1038/s41467-018-06113-4

実験手法

X-RAY DIFFRACTION (3.72 Å)