6EAH

CRYSTAL STRUCTURE OF HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN INHIBITOR ESCAPE VARIANT K394R-S398L STABILIZED IN THE PREFUSION STATE

Summary for 6EAH

• Entry DOI: 10.2210/pdb6eah/pdb
• Descriptor: Fusion glycoprotein F0, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (4 entities in total)
• Functional Keywords: class i viral fusion protein, fusion, respiratory syncytial virus, prefusion, viral protein, fusion inhibitor
• Biological source: Human respiratory syncytial virus
• Total number of polymer chains: 3
• Total formula weight: 192516.41

Authors

Battles, M.B.,McLellan, J.S. (deposition date: 2018-08-03, release date: 2019-08-07, Last modification date: 2024-10-23)

• Primary citation: Battles, M.B.,McLellan, J.S.; Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance; To be published,

Experimental method

X-RAY DIFFRACTION (3 Å)