6E5S

Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II

Summary for 6E5S

Entry DOI	10.2210/pdb6e5s/pdb
Descriptor	Retinol-binding protein 2, RETINAL (3 entities in total)
Functional Keywords	retinol, ilbp, protein switch, cytosolic protein, lipid binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	12
Total formula weight	189340.90
Authors	Nosrati, M.,Ghanbarpour, A.,Geiger, J. (deposition date: 2018-07-22, release date: 2019-07-24, Last modification date: 2023-10-11)
Primary citation	Ghanbarpour, A.,Pinger, C.,Esmatpour Salmani, R.,Assar, Z.,Santos, E.M.,Nosrati, M.,Pawlowski, K.,Spence, D.,Vasileiou, C.,Jin, X.,Borhan, B.,Geiger, J.H. Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches. J.Am.Chem.Soc., 141:17125-17132, 2019 Cited by PubMed: 31557439 DOI: 10.1021/jacs.9b04664 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.061 Å)

Structure validation