6E4E

Crystal structure of dihydrofolate reductase from Staphylococcus aureus MW2 bound to NADP and p218

6E4E の概要

• エントリーDOI: 10.2210/pdb6e4e/pdb
• 分子名称: Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, ... (4 entities in total)
• 機能のキーワード: niaid, dhfr, folate, folic acid, mmv, inhibitor, malaria, structural genomics, seattle structural genomics center for infectious disease, ssgcid, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Staphylococcus aureus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21840.47

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2018-07-17, 公開日: 2018-07-25, 最終更新日: 2023-10-11)

• 主引用文献: Edwards, T.E.,Mayclin, S.J.,Lorimer, D.D.,Horanyi, P.S.,Seattle Structural Genomics Center for Infectious Disease (SSGCID); Crystal structure of dihydrofolate reductase from Staphylococcus aureus MW2 bound to NADP and p218; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)