6E48

Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Lithocholic Acid

Summary for 6E48

• Entry DOI: 10.2210/pdb6e48/pdb
• Related: 3LQ6
• Descriptor: VP1 P domain, CMRF35-like molecule 1, (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid, ... (6 entities in total)
• Functional Keywords: norovirus, capsid protein, protruding domain, bile acid, viral protein, lca, myeloid receptor, cmrf-35-like molecule-1, clm-1, clm1, dir2, irem1, lmir3, pigr3, igsf13
• Biological source: Murine norovirus 1; More
• Total number of polymer chains: 4
• Total formula weight: 92729.11

Authors

Nelson, C.A.,Fremont, D.H. (deposition date: 2018-07-16, release date: 2018-09-12, Last modification date: 2023-10-11)

• Primary citation: Nelson, C.A.,Wilen, C.B.,Dai, Y.N.,Orchard, R.C.,Kim, A.S.,Stegeman, R.A.,Hsieh, L.L.,Smith, T.J.,Virgin, H.W.,Fremont, D.H.; Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.; Proc. Natl. Acad. Sci. U.S.A., 115:E9201-E9210, 2018; PubMed: 30194229; DOI: 10.1073/pnas.1805797115

Experimental method

X-RAY DIFFRACTION (1.801 Å)