6E2J

Crystal structure of the heterocomplex between human keratin 1 coil 1B containing S233L mutation and wild-type human keratin 10 coil 1B

Summary for 6E2J

Entry DOI	10.2210/pdb6e2j/pdb
Descriptor	Keratin, type II cytoskeletal 1, Keratin, type I cytoskeletal 10, SULFATE ION, ... (4 entities in total)
Functional Keywords	intermediate filament, keratin, coiled-coil, skin, protein fibril
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	25296.06
Authors	Eldirany, S.A.,Lomakin, I.B.,Bunick, C.G. (deposition date: 2018-07-11, release date: 2019-05-15, Last modification date: 2024-03-13)
Primary citation	Eldirany, S.A.,Ho, M.,Hinbest, A.J.,Lomakin, I.B.,Bunick, C.G. Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly. Embo J., 38:-, 2019 Cited by PubMed: 31036554 DOI: 10.15252/embj.2018100741 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.386 Å)

Structure validation