6DZO

Crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A with 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site, and (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine at the beta-site

Summary for 6DZO

• Entry DOI: 10.2210/pdb6dzo/pdb
• Related: 4HN4 4HPX 6DZ4
• Descriptor: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (9 entities in total)
• Functional Keywords: q114a, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); More
• Total number of polymer chains: 2
• Total formula weight: 73378.57

Authors

Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L. (deposition date: 2018-07-05, release date: 2019-07-10, Last modification date: 2023-10-11)

• Primary citation: Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L.; Crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A with 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site, and (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine at the beta-site; To be Published,

Experimental method

X-RAY DIFFRACTION (1.64 Å)