6DZO

Crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A with 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site, and (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine at the beta-site

6DZO の概要

• エントリーDOI: 10.2210/pdb6dzo/pdb
• 関連するPDBエントリー: 4HN4 4HPX 6DZ4
• 分子名称: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (9 entities in total)
• 機能のキーワード: q114a, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 73378.57

構造登録者

Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L. (登録日: 2018-07-05, 公開日: 2019-07-10, 最終更新日: 2023-10-11)

• 主引用文献: Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L.; Crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A with 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site, and (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine at the beta-site; To be Published,

実験手法

X-RAY DIFFRACTION (1.64 Å)