6DXS

Crystal structure of the LigJ hydratase E284Q mutant substrate complex with (3Z)-2-keto-4-carboxy-3-hexenedioate

6DXS の概要

• エントリーDOI: 10.2210/pdb6dxs/pdb
• 関連するPDBエントリー: 6DXQ
• 分子名称: 4-oxalomesaconate hydratase, ZINC ION, (2Z)-4-oxobut-2-ene-1,2,4-tricarboxylic acid, ... (4 entities in total)
• 機能のキーワード: hydratase, amidohydrolase, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Sphingobium sp. SYK-6
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 153884.11

構造登録者

Mabanglo, M.F.,Raushel, F.M.,Hogancamp, T.N. (登録日: 2018-06-29, 公開日: 2018-09-26, 最終更新日: 2023-10-11)

• 主引用文献: Hogancamp, T.N.,Mabanglo, M.F.,Raushel, F.M.; Structure and Reaction Mechanism of the LigJ Hydratase: An Enzyme Critical for the Bacterial Degradation of Lignin in the Protocatechuate 4,5-Cleavage Pathway.; Biochemistry, 57:5841-5850, 2018; PubMed: 30207699; DOI: 10.1021/acs.biochem.8b00713

実験手法

X-RAY DIFFRACTION (1.65 Å)