6DWS

Crystal structure of human GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

6DWS の概要

• エントリーDOI: 10.2210/pdb6dws/pdb
• 分子名称: Endoplasmic reticulum chaperone BiP, 8-{[(2-chlorophenyl)methyl]amino}adenosine, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: human grp78, adenosine analog, chaperone, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 85173.69

構造登録者

Chen, Y.,Antoshchenko, T.,Smil, D.,Zepeda, C.,Huang, Y.,Park, H.W. (登録日: 2018-06-27, 公開日: 2019-07-03, 最終更新日: 2024-03-13)

• 主引用文献: Chen, Y.,Antoshchenko, T.,Smil, D.,Zepeda, C.,Huang, Y.,Park, H.W.; Crystal structure of human GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)