6DW0

Cryo-EM structure of the benzodiazepine-sensitive alpha1beta1gamma2S tri-heteromeric GABAA receptor in complex with GABA (Whole map)

Summary for 6DW0

• Entry DOI: 10.2210/pdb6dw0/pdb
• Related: 6DW1
• EMDB information: 8922 8923
• Descriptor: Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric acid receptor subunit alpha-1,Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit beta-1,Gamma-aminobutyric acid receptor subunit beta-1, ... (8 entities in total)
• Functional Keywords: neurotransmission, gaba receptors, gaba, cys loop receptors, ion channel, membrane protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 5
• Total formula weight: 242410.22

Authors

Phulera, S.,Zhu, H.,Yu, J.,Yoshioka, C.,Gouaux, E. (deposition date: 2018-06-26, release date: 2018-08-08, Last modification date: 2023-11-15)

• Primary citation: Phulera, S.,Zhu, H.,Yu, J.,Claxton, D.P.,Yoder, N.,Yoshioka, C.,Gouaux, E.; Cryo-EM structure of the benzodiazepine-sensitive alpha 1 beta 1 gamma 2S tri-heteromeric GABAAreceptor in complex with GABA.; Elife, 7:-, 2018; PubMed: 30044221; DOI: 10.7554/eLife.39383

Experimental method

ELECTRON MICROSCOPY (3.8 Å)