Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF selenomethionine-labelled sigma factor L) with 6 nt spacer

Summary for 6DVE

DescriptorDNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
Functional Keywordsmycobacterium tuberculosis, rna polymerase, ecf sigma factor, transferase, transferase-dna complex, transferase/dna
Biological sourceMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains8
Total molecular weight398367.74
Lin, W.,Das, K.,Feng, Y.,Ebright, R.H. (deposition date: 2018-06-23, release date: 2019-02-20, Last modification date: 2019-02-27)
Primary citation
Lin, W.,Mandal, S.,Degen, D.,Cho, M.S.,Feng, Y.,Das, K.,Ebright, R.H.
Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10:710-710, 2019
PubMed: 30755604 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-019-08443-3
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2497 0.4% 1.4% 4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6dve
no rotation
Molmil generated image of 6dve
rotated about x axis by 90°
Molmil generated image of 6dve
rotated about y axis by 90°