6DV5
Oligomeric complex of a Hsp27 24-mer at 3.6 A resolution
Summary for 6DV5
Entry DOI | 10.2210/pdb6dv5/pdb |
Descriptor | Heat shock protein beta-1 (1 entity in total) |
Functional Keywords | molecular chaperone, small heat shock protein, alpha crystallin domain, chaperone |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 24 |
Total formula weight | 547451.66 |
Authors | Aguda, A.H.,Brayer, G.D. (deposition date: 2018-06-22, release date: 2019-06-26, Last modification date: 2023-10-11) |
Primary citation | Nappi, L.,Aguda, A.H.,Al Nakouzi, N.,Lelj Garolla, B.,Beraldi, E.,Lallous, N.,Thi, M.,Moore, S.,Battsogt, D.,Stoffeliene, S.,Ban, F.,Nguyen, N.T.,Saxena, N.,Dueva, E.,Yamazaki, T.,Zoubeidi, A.,Cherkasov, A.,Brayer, G.D.,Gleave, M. Structure-Guided Discovery of Ivermectin as an Inhibitor of Heat Shock Protein-27 Phosphorylation and Depolymerization. To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.58 Å) |
Structure validation
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