6DTN
The structure of NTMT1 in complex with compound DC100-1
Summary for 6DTN
Entry DOI | 10.2210/pdb6dtn/pdb |
Related PRD ID | PRD_002319 |
Descriptor | N-terminal Xaa-Pro-Lys N-methyltransferase 1, (6D6)PPKRIA(NH2), DC100-1 (3 entities in total) |
Functional Keywords | methyltransferase, enzyme, inhibitor complex, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 28407.38 |
Authors | Noinaj, N.,Chen, D.,Huang, R. (deposition date: 2018-06-18, release date: 2019-04-03, Last modification date: 2023-10-11) |
Primary citation | Chen, D.,Dong, G.,Noinaj, N.,Huang, R. Discovery of Bisubstrate Inhibitors for Protein N-Terminal Methyltransferase 1. J. Med. Chem., 62:3773-3779, 2019 Cited by PubMed: 30883119DOI: 10.1021/acs.jmedchem.9b00206 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.475 Å) |
Structure validation
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