6DTI

Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an unmodifed anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin

Summary for 6DTI

Entry DOI	10.2210/pdb6dti/pdb
Descriptor	16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (25 entities in total)
Functional Keywords	2-thiocytidine, inosine, transfer rna, trna, ribosome, 30s, translation, anticodon
Biological source	Thermus thermophilus HB8 More
Total number of polymer chains	23
Total formula weight	788872.80
Authors	Cantara, W.A.,DeMirci, H.,Agris, P.F. (deposition date: 2018-06-16, release date: 2019-04-24, Last modification date: 2023-10-11)
Primary citation	Vangaveti, S.,Cantara, W.A.,Spears, J.L.,DeMirci, H.,Murphy IV, F.V.,Ranganathan, S.V.,Sarachan, K.L.,Agris, P.F. A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432:913-929, 2020 Cited by PubMed: 31945376 DOI: 10.1016/j.jmb.2019.12.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.54 Å)

Structure validation