6DPQ

Mapping the binding trajectory of a suicide inhibitor in human indoleamine 2,3-dioxygenase 1

Summary for 6DPQ

Entry DOI	10.2210/pdb6dpq/pdb
Related	5WMV 5WMW 5WMX 5WN8 6DPR
Descriptor	Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, GLYCEROL, ... (5 entities in total)
Functional Keywords	indoleamine 2, 3-dioxygenase, heme-containing enzyme, bms-986205, structure-based design, hido1-selective inhibitor, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	97163.80
Authors	Pham, K.N.,Yeh, S.R. (deposition date: 2018-06-09, release date: 2018-11-07, Last modification date: 2023-10-11)
Primary citation	Pham, K.N.,Yeh, S.R. Mapping the Binding Trajectory of a Suicide Inhibitor in Human Indoleamine 2,3-Dioxygenase 1. J. Am. Chem. Soc., 140:14538-14541, 2018 Cited by PubMed: 30347977 DOI: 10.1021/jacs.8b07994 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.94 Å)

Structure validation