6DN7

SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) Cyclic peptide inhibitor

6DN7 の概要

• エントリーDOI: 10.2210/pdb6dn7/pdb
• 関連するBIRD辞書のPRD_ID: PRD_002313
• 分子名称: SPRY domain-containing SOCS box protein 4, WDINNN(BAL) Cyclic peptide inhibitor, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: proteasomal degradation, nitric oxide, inhibitor, immune system, immune system-inhibitor complex, immune system/inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 52219.41

構造登録者

Law, R.H.P.,Caradoc-Davies, T.T.,Norton, R.S. (登録日: 2018-06-06, 公開日: 2019-04-17, 最終更新日: 2020-01-08)

• 主引用文献: Sadek, M.M.,Barlow, N.,Leung, E.W.W.,Williams-Noonan, B.J.,Yap, B.K.,Shariff, F.M.,Caradoc-Davies, T.T.,Nicholson, S.E.,Chalmers, D.K.,Thompson, P.E.,Law, R.H.P.,Norton, R.S.; A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.; ACS Chem. Biol., 13:2930-2938, 2018; PubMed: 30226743; DOI: 10.1021/acschembio.8b00561

実験手法

X-RAY DIFFRACTION (1.4 Å)