6DMQ

Crystal structure of the T27A mutant of human alpha defensin HNP4.

Summary for 6DMQ

• Entry DOI: 10.2210/pdb6dmq/pdb
• Descriptor: Neutrophil defensin 4, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
• Functional Keywords: human alpha-defensin, antimicrobial peptide, antimicrobial protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 8
• Total formula weight: 29641.85

Authors

Gohain, N.,Tolbert, W.D.,Pazgier, M. (deposition date: 2018-06-05, release date: 2019-01-30, Last modification date: 2023-10-11)

• Primary citation: Hu, H.,Di, B.,Tolbert, W.D.,Gohain, N.,Yuan, W.,Gao, P.,Ma, B.,He, Q.,Pazgier, M.,Zhao, L.,Lu, W.; Systematic mutational analysis of human neutrophil alpha-defensin HNP4.; Biochim Biophys Acta Biomembr, 1861:835-844, 2019; PubMed: 30658057; DOI: 10.1016/j.bbamem.2019.01.007

Experimental method

X-RAY DIFFRACTION (1.7 Å)