6DLP

Crystal structure of LRRK2 WD40 domain dimer

Summary for 6DLP

• Entry DOI: 10.2210/pdb6dlp/pdb
• Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2, PLATINUM (II) ION (2 entities in total)
• Functional Keywords: parkinson's disease, lrrk2, wd40, cytosolic protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 88509.47

Authors

Zhang, P.,Ru, H.,Wang, L.,Wu, H. (deposition date: 2018-06-02, release date: 2019-01-09, Last modification date: 2024-03-13)

• Primary citation: Zhang, P.,Fan, Y.,Ru, H.,Wang, L.,Magupalli, V.G.,Taylor, S.S.,Alessi, D.R.,Wu, H.; Crystal structure of the WD40 domain dimer of LRRK2.; Proc. Natl. Acad. Sci. U.S.A., 116:1579-1584, 2019; PubMed: 30635421; DOI: 10.1073/pnas.1817889116

Experimental method

X-RAY DIFFRACTION (4 Å)