6DLP
Crystal structure of LRRK2 WD40 domain dimer
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue PT B 2601 |
| Chain | Residue |
| B | CYS2154 |
| B | CYS2201 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue PT B 2602 |
| Chain | Residue |
| B | CYS2302 |
| B | LEU2303 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue PT B 2603 |
| Chain | Residue |
| B | CYS2418 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue PT A 2601 |
| Chain | Residue |
| A | CYS2418 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue PT A 2602 |
| Chain | Residue |
| A | CYS2302 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue PT A 2603 |
| Chain | Residue |
| A | CYS2154 |
| A | CYS2201 |
Functional Information from PROSITE/UniProt
| site_id | PS00626 |
| Number of Residues | 11 |
| Details | RCC1_2 Regulator of chromosome condensation (RCC1) signature 2. IGTGgGHILLL |
| Chain | Residue | Details |
| B | ILE2427-LEU2437 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"WD 2","evidences":[{"source":"PubMed","id":"38127736","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8FO2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8FO8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8FO9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 88 |
| Details | Repeat: {"description":"WD 5","evidences":[{"source":"PubMed","id":"38127736","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8FO2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8FO8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8FO9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00758","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
