6DK0

Human sigma-1 receptor bound to NE-100

Summary for 6DK0

Entry DOI	10.2210/pdb6dk0/pdb
Descriptor	Sigma non-opioid intracellular receptor 1, N-{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl}-N-propylpropan-1-amine, SULFATE ION, ... (6 entities in total)
Functional Keywords	membrane protein, antagonist bound, receptor, sigma-1 receptor
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	81883.66
Authors	Schmidt, H.R.,Kruse, A.C. (deposition date: 2018-05-28, release date: 2018-10-17, Last modification date: 2023-10-11)
Primary citation	Schmidt, H.R.,Betz, R.M.,Dror, R.O.,Kruse, A.C. Structural basis for sigma1receptor ligand recognition. Nat. Struct. Mol. Biol., 25:981-987, 2018 Cited by PubMed: 30291362 DOI: 10.1038/s41594-018-0137-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation