6DIK
Crystal structure of Bothropstoxin I (BthTX-I) complexed to Chicoric acid
Summary for 6DIK
Entry DOI | 10.2210/pdb6dik/pdb |
Related | 3IQ3 |
Descriptor | Basic phospholipase A2 homolog bothropstoxin-1, (2R,3R)-2,3-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}butanedioic acid, SULFATE ION, ... (6 entities in total) |
Functional Keywords | bothropd jararacussu, bthtx-i, inhibitor, chicoric acid, cichoric acid, pla2, toxin |
Biological source | Bothrops jararacussu (Jararacussu) |
Total number of polymer chains | 2 |
Total formula weight | 28566.07 |
Authors | Cardoso, F.F.,Salvador, G.H.M.,Borges, R.J. (deposition date: 2018-05-23, release date: 2018-10-03, Last modification date: 2023-10-11) |
Primary citation | Cardoso, F.F.,Borges, R.J.,Dreyer, T.R.,Salvador, G.H.M.,Cavalcante, W.L.G.,Pai, M.D.,Gallacci, M.,Fontes, M.R.M. Structural basis of phospholipase A2-like myotoxin inhibition by chicoric acid, a novel potent inhibitor of ophidian toxins. Biochim Biophys Acta Gen Subj, 1862:2728-2737, 2018 Cited by PubMed: 30251662DOI: 10.1016/j.bbagen.2018.08.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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