6DIK

Crystal structure of Bothropstoxin I (BthTX-I) complexed to Chicoric acid

6DIK の概要

• エントリーDOI: 10.2210/pdb6dik/pdb
• 関連するPDBエントリー: 3IQ3
• 分子名称: Basic phospholipase A2 homolog bothropstoxin-1, (2R,3R)-2,3-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}butanedioic acid, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: bothropd jararacussu, bthtx-i, inhibitor, chicoric acid, cichoric acid, pla2, toxin
• 由来する生物種: Bothrops jararacussu (Jararacussu)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28566.07

構造登録者

Cardoso, F.F.,Salvador, G.H.M.,Borges, R.J. (登録日: 2018-05-23, 公開日: 2018-10-03, 最終更新日: 2023-10-11)

• 主引用文献: Cardoso, F.F.,Borges, R.J.,Dreyer, T.R.,Salvador, G.H.M.,Cavalcante, W.L.G.,Pai, M.D.,Gallacci, M.,Fontes, M.R.M.; Structural basis of phospholipase A2-like myotoxin inhibition by chicoric acid, a novel potent inhibitor of ophidian toxins.; Biochim Biophys Acta Gen Subj, 1862:2728-2737, 2018; PubMed: 30251662; DOI: 10.1016/j.bbagen.2018.08.002

実験手法

X-RAY DIFFRACTION (1.93 Å)