6DFI

Crystal structure of anti-Zika antibody Z021 bound to Zika virus envelope protein DIII

6DFI の概要

• エントリーDOI: 10.2210/pdb6dfi/pdb
• 分子名称: anti-Zika antibody Z021, Heavy Chain, anti-Zika antibody Z021, Light Chain, Zika virus envelope protein DIII, ... (4 entities in total)
• 機能のキーワード: antibody, fab, zika, dengue, recurrent, neutralizing, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 60538.82

構造登録者

Keeffe, J.R.,Bjorkman, P.J. (登録日: 2018-05-14, 公開日: 2018-10-24, 最終更新日: 2018-11-14)

• 主引用文献: Keeffe, J.R.,Van Rompay, K.K.A.,Olsen, P.C.,Wang, Q.,Gazumyan, A.,Azzopardi, S.A.,Schaefer-Babajew, D.,Lee, Y.E.,Stuart, J.B.,Singapuri, A.,Watanabe, J.,Usachenko, J.,Ardeshir, A.,Saeed, M.,Agudelo, M.,Eisenreich, T.,Bournazos, S.,Oliveira, T.Y.,Rice, C.M.,Coffey, L.L.,MacDonald, M.R.,Bjorkman, P.J.,Nussenzweig, M.C.,Robbiani, D.F.; A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.; Cell Rep, 25:1385-1394.e7, 2018; PubMed: 30403995; DOI: 10.1016/j.celrep.2018.10.031

実験手法

X-RAY DIFFRACTION (2.48 Å)