6DEK
Crystal structure of Candida albicans acetohydroxyacid synthase catalytic subunit
Summary for 6DEK
Entry DOI | 10.2210/pdb6dek/pdb |
Descriptor | Acetolactate synthase, FLAVIN-ADENINE DINUCLEOTIDE, POTASSIUM ION, ... (6 entities in total) |
Functional Keywords | ahas, acetohydroxyacid synthase, acetolactate synthase, herbicide, thiamin diphosphate, fad, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Total number of polymer chains | 1 |
Total formula weight | 75589.63 |
Authors | Garcia, M.D.,Guddat, L.W. (deposition date: 2018-05-12, release date: 2018-09-26, Last modification date: 2023-10-11) |
Primary citation | Garcia, M.D.,Chua, S.M.H.,Low, Y.S.,Lee, Y.T.,Agnew-Francis, K.,Wang, J.G.,Nouwens, A.,Lonhienne, T.,Williams, C.M.,Fraser, J.A.,Guddat, L.W. Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proc. Natl. Acad. Sci. U.S.A., 115:E9649-E9658, 2018 Cited by PubMed: 30249642DOI: 10.1073/pnas.1809422115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.971 Å) |
Structure validation
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