6DD5

Crystal Structure of the Cas6 Domain of Marinomonas mediterranea MMB-1 Cas6-RT-Cas1 Fusion Protein

6DD5 の概要

• エントリーDOI: 10.2210/pdb6dd5/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900001
• 分子名称: MMB-1 Cas6 Fused to Maltose Binding Protein,CRISPR-associated endonuclease Cas1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: crispr cas protein, endoribonuclease, hydrolase
• 由来する生物種: Escherichia coli O157:H7; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 153068.14

構造登録者

Stamos, J.L.,Mohr, G.,Silas, S.,Makarova, K.S.,Markham, L.M.,Yao, J.,Lucas-Elio, P.,Sanchez-Amat, A.,Fire, A.Z.,Koonin, E.V.,Lambowitz, A.M. (登録日: 2018-05-09, 公開日: 2018-10-17, 最終更新日: 2023-10-11)

• 主引用文献: Mohr, G.,Silas, S.,Stamos, J.L.,Makarova, K.S.,Markham, L.M.,Yao, J.,Lucas-Elio, P.,Sanchez-Amat, A.,Fire, A.Z.,Koonin, E.V.,Lambowitz, A.M.; A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition.; Mol. Cell, 72:700-, 2018; PubMed: 30344094; DOI: 10.1016/j.molcel.2018.09.013

実験手法

X-RAY DIFFRACTION (2.85 Å)