6DCW
Crystal structure of human anti-tau antibody CBTAU-27.1 Fab in complex with a human tau peptide
Summary for 6DCW
Entry DOI | 10.2210/pdb6dcw/pdb |
Descriptor | Light chain of CBTAU27.1 Fab, Heavy chain of CBTAU27.1 Fab, tau peptide, ... (4 entities in total) |
Functional Keywords | tau, fab, naturally occurring human antibody, common motif, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 51487.27 |
Authors | Zhu, X.,Zhang, H.,Wilson, I.A. (deposition date: 2018-05-08, release date: 2018-06-06, Last modification date: 2023-10-11) |
Primary citation | Apetri, A.,Crespo, R.,Juraszek, J.,Pascual, G.,Janson, R.,Zhu, X.,Zhang, H.,Keogh, E.,Holland, T.,Wadia, J.,Verveen, H.,Siregar, B.,Mrosek, M.,Taggenbrock, R.,Ameijde, J.,Inganas, H.,van Winsen, M.,Koldijk, M.H.,Zuijdgeest, D.,Borgers, M.,Dockx, K.,Stoop, E.J.M.,Yu, W.,Brinkman-van der Linden, E.C.,Ummenthum, K.,van Kolen, K.,Mercken, M.,Steinbacher, S.,de Marco, D.,Hoozemans, J.J.,Wilson, I.A.,Koudstaal, W.,Goudsmit, J. A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities. Acta Neuropathol Commun, 6:43-43, 2018 Cited by PubMed: 29855358DOI: 10.1186/s40478-018-0543-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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