6DCC

Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA

6DCC の概要

• エントリーDOI: 10.2210/pdb6dcc/pdb
• 分子名称: 7SK snRNA methylphosphate capping enzyme, human 7SK RNA stem-loop 1 proximal methylated, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
• 機能のキーワード: rna methyl transferase, mepce, 7sk rna, transferase-rna complex, transferase/rna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47327.12

構造登録者

Yang, Y.,Eichhorn, C.,Cascio, D.,Feigon, J. (登録日: 2018-05-04, 公開日: 2018-12-19, 最終更新日: 2023-10-11)

• 主引用文献: Yang, Y.,Eichhorn, C.D.,Wang, Y.,Cascio, D.,Feigon, J.; Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE.; Nat. Chem. Biol., 15:132-140, 2019; PubMed: 30559425; DOI: 10.1038/s41589-018-0188-z

実験手法

X-RAY DIFFRACTION (2.1 Å)