6DC6

Crystal structure of human ubiquitin activating enzyme E1 (Uba1) in complex with ubiquitin

6DC6 の概要

• エントリーDOI: 10.2210/pdb6dc6/pdb
• 分子名称: Ubiquitin-like modifier-activating enzyme 1, Ubiquitin, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: ubiquitin, e1, adenylation, thioester bond, e2, transthiolation, signaling protein, signaling protein-ligase complex, signaling protein/ligase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 245272.96

構造登録者

Lv, Z.,Yuan, L.,Williams, K.M.,Atkison, J.H.,Olsen, S.K. (登録日: 2018-05-04, 公開日: 2018-10-10, 最終更新日: 2023-10-11)

• 主引用文献: Lv, Z.,Williams, K.M.,Yuan, L.,Atkison, J.H.,Olsen, S.K.; Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity.; J. Biol. Chem., 293:18337-18352, 2018; PubMed: 30279270; DOI: 10.1074/jbc.RA118.003975

実験手法

X-RAY DIFFRACTION (3.14 Å)