6DAV

Crystal Structure of Human DHFR complexed with NADP and N10formyltetrahydrofolate

6DAV の概要

• エントリーDOI: 10.2210/pdb6dav/pdb
• 分子名称: Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, N-(4-{[(2,4-diaminopteridin-6-yl)methyl](hydroxymethyl)amino}benzene-1-carbonyl)-L-glutamic acid, ... (5 entities in total)
• 機能のキーワード: structure-guided drug discovery consortium, dihydrofolate reductase, hdhfr, nadp, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Mitochondrion : P00374
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 45575.34

構造登録者

Mayclin, S.J.,Dranow, D.M.,Lorimer, D.D. (登録日: 2018-05-02, 公開日: 2018-05-16, 最終更新日: 2024-03-13)

• 主引用文献: Mayclin, S.J.,Dranow, D.M.,Walpole, C.,Lorimer, D.D.; Crystal Structure of Human DHFR complexed with NADP and N10formyltetrahydrofolate; to be published,

実験手法

X-RAY DIFFRACTION (1.55 Å)