6D83
Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric subunit
Summary for 6D83
Entry DOI | 10.2210/pdb6d83/pdb |
EMDB information | 7453 |
Descriptor | Bone marrow stromal antigen 2,Protein Nef, AP-1 complex subunit beta-1, ADP-ribosylation factor 1, ... (8 entities in total) |
Functional Keywords | ap, hiv, nef, trafficking, protein transport |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 306758.51 |
Authors | Buffalo, C.Z.,Morris, K.L.,Hurley, J.H. (deposition date: 2018-04-25, release date: 2018-08-08, Last modification date: 2024-03-13) |
Primary citation | Morris, K.L.,Buffalo, C.Z.,Sturzel, C.M.,Heusinger, E.,Kirchhoff, F.,Ren, X.,Hurley, J.H. HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174:659-671.e14, 2018 Cited by PubMed: 30053425DOI: 10.1016/j.cell.2018.07.004 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.27 Å) |
Structure validation
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