6D74

Direct Activation of the Executioner Domain of MLKL by a Select Repertoire of Inositol Phosphates

Summary for 6D74

• Entry DOI: 10.2210/pdb6d74/pdb
• NMR Information: BMRB: 30458
• Descriptor: Mixed lineage kinase domain-like protein (1 entity in total)
• Functional Keywords: membrane, lipid binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 18318.13

Authors

Royappa, G.C.,McNamara, D.E.,Moldoveanu, T. (deposition date: 2018-04-24, release date: 2019-05-15, Last modification date: 2023-06-14)

• Primary citation: McNamara, D.E.,Dovey, C.M.,Hale, A.T.,Quarato, G.,Grace, C.R.,Guibao, C.D.,Diep, J.,Nourse, A.,Cai, C.R.,Wu, H.,Kalathur, R.C.,Green, D.R.,York, J.D.,Carette, J.E.,Moldoveanu, T.; Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.; Cell Chem Biol, 26:863-, 2019; PubMed: 31031142; DOI: 10.1016/j.chembiol.2019.03.010

Experimental method

SOLUTION NMR