6D74
Direct Activation of the Executioner Domain of MLKL by a Select Repertoire of Inositol Phosphates
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007166 | biological_process | cell surface receptor signaling pathway |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 148 |
| Details | Region: {"description":"N-terminal bundle and brace (NBB); mediates INSP6 binding","evidences":[{"source":"PubMed","id":"29883610","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 29 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Target of necrosulfonamide inhibitor","evidences":[{"source":"PubMed","id":"22265413","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
