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6D3G

PER-2 class A extended-spectrum beta-lactamase crystal structure in complex with avibactam at 2.4 Angstrom resolution

Summary for 6D3G
Entry DOI10.2210/pdb6d3g/pdb
DescriptorBeta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, TETRAETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywordsdbo, penicilloil-serine-transferase, antibiotic resistance, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceCitrobacter freundii
Total number of polymer chains4
Total formula weight125088.58
Authors
Power, P.,Ruggiero, M.,Gutkind, G.,Bonomo, R.,Klinke, S. (deposition date: 2018-04-16, release date: 2019-04-24, Last modification date: 2023-10-04)
Primary citationRuggiero, M.,Papp-Wallace, K.M.,Brunetti, F.,Barnes, M.D.,Bonomo, R.A.,Gutkind, G.,Klinke, S.,Power, P.
Structural Insights into the Inhibition of the Extended-Spectrum beta-Lactamase PER-2 by Avibactam.
Antimicrob.Agents Chemother., 63:-, 2019
Cited by
PubMed: 31235626
DOI: 10.1128/AAC.00487-19
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.398 Å)
Structure validation

217705

건을2024-03-27부터공개중

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