6D1M
Design, synthesis, and X-ray of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects
Summary for 6D1M
| Entry DOI | 10.2210/pdb6d1m/pdb |
| Descriptor | Carbonic anhydrase 2, ZINC ION, 4-(cyclohexylselanyl)benzene-1-sulfonamide, ... (5 entities in total) |
| Functional Keywords | carbonic anhydrase inhibitors, neuropathic pain, selenium, metalloenzymes, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 30083.15 |
| Authors | Peat, T.S.,Angeli, A.,di Cesare Mannelli, L.,Micheli, L.,Ghelardini, C.,Supuran, C.T. (deposition date: 2018-04-12, release date: 2018-06-13, Last modification date: 2023-10-04) |
| Primary citation | Angeli, A.,di Cesare Mannelli, L.,Lucarini, E.,Peat, T.S.,Ghelardini, C.,Supuran, C.T. Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects. Eur J Med Chem, 154:210-219, 2018 Cited by PubMed: 29803994DOI: 10.1016/j.ejmech.2018.05.026 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.21 Å) |
Structure validation
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