6D1L
Design, synthesis, and X-ray of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects
Summary for 6D1L
Entry DOI | 10.2210/pdb6d1l/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | carbonic anhydrase inhibitors, neuropathic pain, selenium, metalloenzymes, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 30023.02 |
Authors | Peat, T.S.,Angeli, A.,di Cesare Mannelli, L.,Micheli, L.,Ghelardini, C.,Supuran, C.T. (deposition date: 2018-04-12, release date: 2018-06-13, Last modification date: 2023-10-04) |
Primary citation | Angeli, A.,di Cesare Mannelli, L.,Lucarini, E.,Peat, T.S.,Ghelardini, C.,Supuran, C.T. Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects. Eur J Med Chem, 154:210-219, 2018 Cited by PubMed: 29803994DOI: 10.1016/j.ejmech.2018.05.026 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
Download full validation report