6D12

Crystal structure of C-terminal xRRM domain of human Larp7 bound to 7SK stem-loop 4 RNA

Summary for 6D12

• Entry DOI: 10.2210/pdb6d12/pdb
• Descriptor: La-related protein 7, human 7SK RNA stem-loop 4 (3 entities in total)
• Functional Keywords: rna recognition motif, rrm, rna apical loop, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 38309.56

Authors

Eichhorn, C.D.,Cascio, D.,Sawaya, M.R.,Feigon, J. (deposition date: 2018-04-11, release date: 2018-06-27, Last modification date: 2020-01-15)

• Primary citation: Eichhorn, C.D.,Yang, Y.,Repeta, L.,Feigon, J.; Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7.; Proc. Natl. Acad. Sci. U.S.A., 115:E6457-E6466, 2018; PubMed: 29946027; DOI: 10.1073/pnas.1806276115

Experimental method

X-RAY DIFFRACTION (2.205 Å)